Neurotoxin

Not every muscle or person is the same and with that in there are 3 different types of neurotoxins are offered: Botox, Dysport, and Daxxify. Neurotoxin or neuromodulators are purified and stabilized molecules derived from C. botulinum used to temporary paralyze the depressor muscles smoothing the appearance of fine lines and wrinkles giving an overall younger appearance.

Botox

Botox is made by Allergan. It’s well-known by name and by being the first brand to develop and patent with FDA approval since the 1970’s to use neurotoxin in order to temporary decrease the appearance wrinkles.

Patient’s may start to see results within 48 hours of injection, however, will take up to 2 weeks for full muscle paralysis.

These results last for approximately 3 months in total duration.

Preparing for the appointment

Come to your appointment with a clean face. Avoid alcohol 12-24 hours before. Limit the amount of caffeine the day of. If you take NSAIDs daily, stop for 24-48 hours before. Avoid foods containing If you take blood thinners, consult with your physician about stopping 48 hours before to limit bruising. If not contraindicated, consider taking Arnica or vitamin K, 1 week before. Avoid harsh exfoliating treatments, facial waxing appointments, chemical peels, or anything that can irritate your skin at least 3 days before. Get your daily workout in before your appointment.

Dysport

Dysport is made by Galderma. Dysport is a newer neurotoxin on the market that is known for a quicker onset and lasts for a longer duration. This is a more concentrated neurotoxin which is states that the onset can be as soon as 48-72 hours and can last up to 4 months. Dysport is one of the neuromodulators that is recommended to those that are athletes or have high metabolism.

Choosing which product

During your consultation, the 3 types will be discussed, if you are currently using a certain product and notice that you are requiring more and more units or feel that its not lasting as long, it will be recommended to switch brands. The education of the brands will be given and will be collaborative decision between provider and patient. All brands are the same price and calculated on a Botox equivalent scale. Price is per unit, not per area.

Daxxify

Daxxify is made by Revance. Daxxify is the newest neurotoxin on the market. This neurotoxin is different because of the science behind it. All other neuromodulators on the market stabilize the C. botulinum with human serum albumin protein; whereas, Daxxify uses a stabilizing peptide instead. This allows for a longer duration as the excess does not get cleared through right away.

The newest studies are showing a duration of 4-5 months with their FDA approved dosing recommendations. The onset can be seen as early as 48 hours. Daxxify is another neuromodulators that is recommended to those that are athletes or have high metabolism.

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Touch-ups

Touch-ups are done 2-3 weeks after initial injection. Even if a newer neurotoxin is use with a quicker onset, it is still recommended to wait the full 2 weeks before any touch-ups are done. This is because the mechanism of action of the medication. Acetylcholine is the neurotransmitter that is used for muscle contraction. Neurotoxin blocks the binding affects of acetylcholine, which paralyzes the muscle. Every muscle is different, some contain more or less acetylcholine than others; therefore, in the 2-week duration, some muscles can be affected sooner or later than others. Since the charge is per unit and not per area, touch-ups are charged as per unit, same as initial injection.

Post injection care/precautions

Avoid touching or massaging the areas injected that day. Avoid wearing hats if forehead was injected for 24 hours. Avoid sleeping on your face the evening of. Avoid saunas, hot tubs, and vigorous exercise for 24 hours.

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